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I sat down a few months ago, and asked myself what sacrifices I could

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

make that would allow me to increase my advertising budget for my inte

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

net network marketing business.

The First Sacrifice:

I was a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

1/2 pack a day smoker. I had tried to quit many times in the past, bu

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

was unsuccessful. It is a hard addiction to get rid of.

But this tim

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

it was much easier, because I found something that motivates me more

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

han anything in the world, and that is money. I quit smoking for the l

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ve of money.

This would save me over $160 a month. To reward my self

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

use that extra money to help me make more money, by using it to incre

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

se my advertising budget.

The Second Sacrifice:

The second th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ng I sacrificed was dining out so much. My wife and I used to only din

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e out. Dining out was our third largest expense each month.

We decide

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

this was not healthy nor financially wise to do so. We both made the

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ecision to decrease the amount of money we spent on dining out so much

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

for breakfast, lunch and dinner.

Just my lunches alone on a $6.00 a d

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

y average, adds up to $180 a month. My Wife’s were much higher, becaus

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

she had to provide for her, my daughter, and her younger brother.

S

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e now enjoys taking that money she saves from not eating out so much a

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d spending it on my daughter and herself.

So.... Just by finding smal

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

sacrifices, you to could increase your advertising budget by hundreds

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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