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Are you unhappy at work – tired of the monotony and lack of opportunity, fed up with commuting miles every day? Sick of the weekends spent shopping and doing housewo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rk, leaving very little time for enjoyment before the whole thing starts again?

If this scenario is familiar, you may be feeling stuck – trapped in a job you hate,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

but too tired to do anything about it.

Here is one possible strategy to begin your search for a more fulfilling career and a more balanced life. Take time to do som

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ething you enjoy, and then do this on a regular basis Next, set aside some time to think about what you really want and finally, investigate the steps you need to ta

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ke in order to achieve it.

The first part of this plan may seem unrelated to the end goal, but is based on the fact that doing things you enjoy makes you feel bette

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

r, gives you more energy and enables you to think about life from a positive angle. Planning a new career is a major task and requires energy, vision and determinati

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

on; qualities which are probably in low supply when you reach the end of a busy week.

Begin by making a list of some of your favourite activities – but be sure they

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

are things you can do without too much effort. Hang-gliding or snowboarding take a bit of organization and aren’t necessarily things you can do regularly – at the m

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

oment. You might choose writing, reading a good novel, exercising, playing with your children, dancing, cooking, listening to music or watching a great movie. Next,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

find a way of building these activities into your routine, if possible making time for at least one of them every day. If there are less interesting ways in which yo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

spend your free time, such as watching all the soaps, or having a beer too many at the pub, cut back a bit to make time for things you actually enjoy. It should be

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

possible to find time every day to read a few pages of a book or listen to one or two tracks by your favourite singer or composer.

Once you are feeling more upbeat,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

set aside a day at the weekend or take a day’s leave to look at what you really want in life. If you already know the direction in which you would like your career

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to go, make enquiries about training courses or look into ways in which you could gain the necessary experience.

If you know you want something different, but don’t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

know what it is, make a list of the things you enjoy about your job and any jobs you’ve had in the past. If you don’t enjoy any aspect of your current position, lis

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t all the things you hate and then write the opposite, in other words, what you’d rather be doing instead.

Other questions to ask yourself are: What would I do if I

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

knew I couldn’t fail? And What would I do if money wasn’t a problem?

Look back at the dreams you had when you were younger – it may be possible to reactivate them.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Often, we end up in jobs because we have bills to pay and the dream is forgotten. Moving to the dream job may take time and the dream itself may need some restructu

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ring. Find one small activity which reconnects you to your dream and do it now.

If you keep a notebook and add your answers to these questions over time, you will s

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ee a pattern emerging and you will gradually be able to build up a picture of your ideal job and the steps you need to take in order to get it.

© Waller Jamison 200

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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